Mathieu FOSSÉPRÉ

Email: Mathieu.FOSSEPRE@umons.ac.be
Phone: 065/37.38.67

Mathieu Fossépré studied Chemistry at the University of Namur (Belgium). In January 2016, he received a PhD from the same university entitled “On the intrinsic flexibility of the µ opioid receptor through multiscale modeling approaches” under the supervision of Prof. Daniel P. Vercauteren (University of Namur, Belgium) and Prof. Aatto Laaksonen (Stockholm University, Sweden). The purpose of his PhD work was mainly focused on understanding the dynamic properties of the µ opioid receptor (µOR), a key protein in the medical field as the target of most used anesthesia. To do so, molecular simulations methods were used. This work resulted in the development of original multiscale models aimed at describing the modularity and the spatial hierarchy of the flexibility properties of µOR.
After a short term project on the dimerization of fluorescent proteins studied with Brownian Dynamics simulations, still in the University of Namur, he has joined the University of Mons as Postdoctoral fellow in June 2016. His research topics deal with the study of molecular interactions between polymers and DNA chains using molecular simulations techniques such as Molecular Dynamics at different spatial resolutions (all-atom, coarse-grained, hybrid). 
Publications
On the modularity of the intrinsic flexibility of the µ opioid receptor: a computational study. Fossépré M., Leherte L., Laaksonen A., Vercauteren D.P., PLoS ONE 9 (2014), e115856.
Design of multiscale coarse-grained elastic network-based potentials for the µ opioid receptor. Fossépré M., Leherte L., Laaksonen A., Vercauteren D.P., submitted (2016).
Multi-graining: a modular- and multi-resolution approach for describing the flexibility of the µ opioid receptor. Fossépré M., Leherte L., Laaksonen A., Vercauteren D.P., submitted (2016).
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